Rieke Lab Publications



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Zylberberg, J., Cafaro, J., Turner, M.H., Shea-brown, E., & Rieke, F. Direction-Selective Circuits Shape Noise to Ensure a Precise Population Code. Neuron 89, 369-383. 2016. [Pdf].


Hass, C.A., Angueyra, J.M., Lindbloom-Brown, Z., Rieke, F., & Horwitz, G.D. Chromatic detection from cone photoreceptors to V1 neurons to behavior in rhesus monkeys. Journal of Vision 15, 1. 2015. [Pdf].

Hoon, M., Sinha, R., Okawa, H., Suzuki, S.C., Hirano, A.A., Brecha, N., Rieke, F., & Wong, R.O.L. Neurotransmission plays contrasting roles in the maturation of inhibitory synapses on axons and dendrites of retinal bipolar cells. PNAS 112, 12840-5. 2015. [Pdf].

Manookin, M.B., Puller, C., Rieke, F., Neitz, J., & Neitz, M. Distinctive receptive field and physiological properties of a wide-field amacrine cell in the macaque monkey retina. J. Neurophysiol. 114, 1606-16. 2015. [Pdf].

Grimes, W.N., Graves, L.R., Summers, M.T., & Rieke, F. A simple retinal mechanism contributes to perceptual interactions between rod- and cone-mediated responses in primates. eLife 4:e08033. 2015. [Pdf].

Grimes, W.N., Zhang, J., Tian, H., Graydon, C.W., Hoon, M., Rieke, F., & Diamond, J.S. Complex inhibitory microcircuitry regulates retinal signaling near visual threshold. J. Neurophysiol. 114, 341-353. 2015. [Pdf].

Azevedo, A.W., Doan, T., Moaven, H., Sokal, I., Baameur, F., Vishnivetskiy, S. a, Homan, K.T., Tesmer, J.J.G., Gurevich, V. V, Chen, J., & Rieke, F. C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor. eLife 4:e05981. 2015. [Pdf].

Puller, C., Manookin, M. B., Neitz, J., Rieke, F., & Neitz, M. Broad Thorny Ganglion Cells: A Candidate for Visual Pursuit Error Signaling in the Primate Retina. Journal of Neuroscience, 35(13), 5397-5408. 2015. [Pdf].

Ala-Laurila, P., & Rieke, F. Coincidence Detection of Single-Photon Responses in the Inner Retina at the Sensitivity Limit of Vision. Current Biology, 24(24), 2888-2898. 2014. [Pdf].

Trenholm, S., Mclaughlin, A. J., Schwab, D. J., Turner, M. H., Smith, R. G., Rieke, F., & Awatramani, G. B. Nonlinear dendritic integration of electrical and chemical synaptic inputs drives fine-scale correlations. Nature Neuroscience, 17, 1759-1766. 2014. [Pdf].

Grimes, W. N., Hoon, M., Briggman, K. L., Wong, R. O., & Rieke, F. Cross-synaptic synchrony and transmission of signal and noise across the mouse retina. eLife, 3:e03892. 2014. [Pdf].

Grimes, W. N., Schwartz, G. W., & Rieke, F. The Synaptic and Circuit Mechanisms Underlying a Change in Spatial Encoding in the Retina. Neuron, 82(2), 460-473. 2014. [Pdf].

Okawa, H., Della Santina, L., Schwartz, G. W., Rieke, F., & Wong, R. O. L. Interplay of Cell-Autonomous and Nonautonomous Mechanisms Tailors Synaptic Connectivity of Converging Axons In Vivo. Neuron, 82(1), 125-137. 2014. [Pdf].

Bleckert, A., Schwartz, G.W., Turner, M.H., Rieke, F., and Wong, R.O.L. Visual Space Is Represented by Nonmatching Topographies of Distinct Mouse Retinal Ganglion Cell Types. Curr. Biol. 24, 310-315. 2014. [Pdf].

Angueyra, J.M., and Rieke, F. Origin and effect of phototransduction noise in primate cone photoreceptors. Nat. Neurosci. 16, 1692-1700. 2013. [Pdf].

Schwartz, G.W., and Rieke, F. Controlling gain one photon at a time. Elife, 2:e00467. 2013. [Pdf].

Cafaro, J., and Rieke, F. Regulation of Spatial Selectivity by Crossover Inhibition. J. Neurosci. 33, 6310-6320. 2013. [Pdf].

Schwartz, G.W., Okawa, H., Dunn, F. A, Morgan, J.L., Kerschensteiner, D., Wong, R.O., and Rieke, F. The spatial structure of a nonlinear receptive field. Nat. Neurosci. 15, 1572-1580. 2012. [Pdf].

Ala-Laurila, P., Greschner, M., Chichilnisky, E.J., and Rieke, F. Cone photoreceptor contributions to noise and correlations in the retinal output. Nat. Neurosci. 14, 1309-1316. 2011. [Pdf].

Schwartz, G., and Rieke, F. Nonlinear spatial encoding by retinal ganglion cells: when 1 + 1 ≠ 2. J. Gen. Physiol. 138, 283-290. 2011. [Pdf].

Murphy, G.J., and Rieke, F. Electrical synaptic input to ganglion cells underlies differences in the output and absolute sensitivity of parallel retinal circuits. J. Neurosci. 31, 12218-12228. 2011. [Pdf].

Azevedo A, and Rieke F. Experimental conditions alter phototransduction: the implications for retinal processing at visual threshold. J. Neurosci. 31(10):3670-3682. 2011. [Pdf], Suppl Table, Supp Fig


Cafaro J, Rieke F. Noise correlations improve response fidelity and stimulus encoding. Nature, 468:964-7, 2010.

Okawa H, Pahlberg J, Rieke F, Birnbaumer L, Sampath AP. Coordinated control of sensitivity by two splice variants of Gα(o) in retinal ON bipolar cells. J Gen Physiol. 136:443-54. 2010.

Tian M, Jarsky T, Murphy GJ, Rieke F, Singer JH. Voltage-gated Na channels in AII amacrine cells accelerate scotopic light responses mediated by the rod bipolar cell pathway. J Neurosci 30:4650-59, 2010.

Rieke F, Rudd ME. The challenges natural images pose for visual adaptation. Neuron 64:605-616, 2009.

Doan T, Azevedo AW, Hurley JB, Rieke F. Arrestin competition influences the kinetics and variability of the single photon response of mammalian rod photoreceptors. J Neurosci 29:11867-11879, 2009.

Wark B, Fairhall AL, Rieke F. Timescales of inference in visual adaptation. Neuron. 61:750-761, 2009.

Shlens, Rieke F, Chichilnisky, EJ. Synchronized firing in the retina. Curr Opin Neurobiol, 18:396-402, 2008.

Rieke F, Lee A, Haeseleer, F. Characterization of Ca2+-binding protein 5 knockout mouse retina. IOVS 49:5126-5135, 2008.

Khuk Trong P, Rieke F. Origin of correlated activity between parasol retinal ganglion cells. Nat Neurosci, 11:1343-1351, 2008.

Dunn FA, Rieke F. Single photon absorptions evoke synaptic depression in the retina to extend the operational range of rod vision. Neuron, 57(6):894-904.

Murphy GJ, Rieke F. Signals and noise in an inhibitory interneuron diverge to control activity in nearby retinal ganglion cells.Nature Neuroscience, 11:318-326, 2008.

Soo F, Detwiler PB, Rieke F. Light adaptation in salamander L cone photoreceptors. J Neurosci, 28:1331-42, 2008.

Dunn, FD, Lankheet ML, Rieke F. Light adaptation in cone vision involves switching between receptor and post-receptor sites. Nature, 449:603-6, 2007. [Pdf, Supp]

Zhang H, Li S, Doan T, Rieke F, Detwiler PB, Frederick JM, Baehr W. Deletion of PrBP/delta impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments.
Proc Natl Acad Sci U S A. 2007 May 22;104(21):8857-62. Epub 2007 May 11. [Pdf]

Murphy GJ, Rieke F. Network variability limits stimulus-evoked spike timing precision in retinal ganglion cells. Neuron. 2006 Nov 9;52(3):511-24. [Pdf]

Doan T, Mendez A, Detwiler PB, Chen J, Rieke F. Multiple phosphorylation sites confer reproducibility of the rod's single-photon responses. Science. 2006 Jul 28;313(5786):3959-70. [Pdf]

Dunn FA, Rieke F. The impact of photoreceptor noise on retinal gain controls. Curr Opin Neurobiol. 2006 Aug;16(4):363-70. [Pdf]

Duncan JL, Yang H, Doan T, Silverstein RS, Murphy GJ, Nune G, Liu X, Copenhagen D, Tempel BL, Rieke F, Krizaj D. Scotopic visual signaling in the mouse retina is modulated by high-affinity plasma membrane calcium extrusion. J Neurosci. 2006 Jul 5;26(27):7201-11
. [Pdf]

Dunn FA, Doan T, Sampath AP, Rieke F. Controlling the gain of rod-mediated signals in the Mammalian retina. J Neurosci. 2006 Apr 12;26(15):3959-70. [Pdf]


Batten ML, Imanishi Y, Tu DC, Doan T, Zhu L, Pang J, Glushakova L, Moise AR, Baehr W, Van Gelder RN, Hauswirth WW, Rieke F, Palczewski K. Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis. PLoS Med. 2005 Nov;2(11):e333. Epub 2005 Nov 1 [Pdf]

Caruso G, Khanal H, Alexiades V, Rieke F, Hamm HE, DiBenedetto E. Mathematical and computational modelling of spatio-temporal signalling in rod phototransduction. Syst Biol (Stevenage). 2005 Sep;152(3):119-37. [Pdf]

Sampath AP, Strissel KJ, Elias R, Arshavsky VY, McGinnis JF, Chen J, Kawamura S, Rieke F, Hurley JB. Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina. Neuron. 2005 May 5;46(3):413-20. [Pdf]

Maeda A, Maeda T, Imanishi Y, Kuksa V, Alekseev A, Bronson JD, Zhang H, Zhu L, Sun W, Saperstein DA, Rieke F, Baehr W, Palczewski K. Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. J Biol Chem. 2005 May 13;280(19):18822-32. Epub 2005 Mar 8. [Pdf]

Field, G.D., Sampath, A.P., Rieke, F. Retinal Processing Near Absolute Threshold: From Behavior to Mechanism. Anuual Review Physiol, 2005;67:491-514. Review. [Pdf]

Chichilnisky EJ, Rieke F. Detection sensitivity and temporal resolution of visual signals near absolute threshold in the salamander retina. J Neurosci. 2005 Jan 12;25(2):318-30. [Pdf]

Haeseleer F, Imanishi Y, Maeda T, Possin DE, Maeda A, Lee A, Rieke F, Palczewski K. Essential role of Ca2+-binding protein 4, a Cav1.4 channel regulator, in photoreceptor synaptic function. Nat Neurosci. 2004 Oct;7(10):1079-87. Epub 2004 Sep 26. [Pdf]

Sampath AP, Rieke F. Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse. Neuron. 2004 Feb 5;41(3):431-43. [Pdf]

Armstrong-Gold CE, Rieke F. Bandpass filtering at the rod to second-order cell synapse in salamander (Ambystoma tigrimun) retina. J Neurosci. 2003 May 1:23(9):3796-806. [Pdf]

Kim KJ, Rieke F. Slow Na+ inactivation and variance adaptation in salamander retinal ganglion cells. J Neurosci. 2003 Feb 15;23(4):1506-16. J Neurosci. 2003 Feb 15;23(4):1506-16. [Pdf]

Brockerhoff SE, Rieke F., Matthews HR, Taylor MR, Kennedy B, Ankoudinova I, Niemi GA, Tucker CL, Xiao M, Cilluffo MC, Fain GL, Hurley JB. Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and suppression of current in cones from the zebrafish mutant nof. J Neurosci. 2003 Jan 15;23(2):470-80. [Pdf]

Field, G.D. and Rieke, F. Mechanisms regulating variability of the single photon responses of mammalian rod photoreceptors. Neuron, 35:733-747, 2002 [Pdf]

Field, G.D. and Rieke, F. Nonlinear signal transfer from mouse rods to bipolar cells and implications for visual sensitivity. Neuron, 34:773-785, 2002. [Pdf]

Howes, K. A., Pennesi, M., Sokal, I., Church-Kopish, J., Schmidt, B, Margolis, D., Frederick, J., Rieke, F., Palczewski, K., Wu, S. M.,Detwiler, P. B., and Baehr, W. GCAP1 rescues rod photoreceptor response in GCAP1/GCAP2 knockout mice. EMBO Journal, 21:1545-1554, 2002. [Pdf]

Van Hooser, J. P., Maeda, T., Kuksa, V., Jang, G-F, He, Y-G, Rieke, F., Fong, H.K.W., Detwiler, P.B., and Palczewski, K. Recovery of visual functions in a Mouse Model of Leber Congenital Amaurosis. J. Biol. Chem., 277:19173-19182, 2002. [Pdf]

Kim, K.J. and Rieke, F. Temporal contrast adaptation in the input and output signals of salamander retinal ganglion cells. J. Neurosci., 21:287-299, 2001. [Pdf]

Rieke, F. Temporal contrast adaptation in salamander bipolar cells. J. Neurosci., 21: 9445-9454, 2001. [Pdf]


Rieke, F. and Baylor, D.A. Origin and functional impact of dark noise in retinal cones. Neuron, 26:181-186, 2000. [Pdf]

Rieke, F. Mechanisms of single-photon detection in rod photoreceptors. Methods Enzymol. 2000;316:186-202.

Rieke, F. Opening the third eye. Nat Neurosci. 1998 Sep;1(5):339-41. [Pdf]

Rieke, and Baylor, D.A. Origin of reproducibility in the responses of retinal rods to single photons. Biophys. J.. 75:1836-1857, 1998. [Pdf]

Rieke, and Baylor, D.A. Single photon detection by rod cells of the retina. Rev. Modern Physics 70:1027-1036, 1998. [Pdf]

Rieke, and Baylor, D.A. Molecular origin of continuous dark noise in rod photoreceptors. Biophys. J. 71:2553-2572, 1996. [Pdf]

Rieke, and Schwartz, E.A. Asynchronous transmitter release: Control of exocytosis and endocytosis at the rod synapse. J. Physiol. 493:1-8, 1996. [Pdf]

Rieke F, Bodnar DA, Bialek W. Naturalistic stimuli increase the rate and efficiency of information transmission by primary auditory afferents. Proc R Soc Lond B Biol Sci. 1995 Dec 22;262(1365):259-65. [Pdf]

Rieke F, Schwartz EA. A cGMP-gated current can control exocytosis at cone synapses. Neuron. 1994 Oct;13(4):863-73. [Pdf]

Bialek W, Rieke F. Reliability and information transmission in spiking neurons. Trends Neurosci. 1992 Nov;15(11):428-34. Review.

Bialek W, Rieke F, de Ruyter van Steveninck RR, Warland D. Reading a neural code. Science. 1991 Jun 28;252(5014):1854-7. [Pdf]